The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Sep. 19, 2014
Applicants:

Georgia Tech Research Corporation, Atlanta, GA (US);

University of Pittsburgh-of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Yu-Ying Liu, Santa Clara, CA (US);

Hiroshi Ishikawa, Wexford, PA (US);

James Rehg, Atlanta, GA (US);

Joel S. Schuman, Pittsburgh, PA (US);

Gadi Wollstein, Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16H 50/50 (2018.01); G16H 10/60 (2018.01); G16H 50/20 (2018.01); A61B 5/00 (2006.01); G06N 5/02 (2006.01);
U.S. Cl.
CPC ...
G16H 50/50 (2018.01); A61B 5/4842 (2013.01); G06N 5/022 (2013.01); G16H 10/60 (2018.01); G16H 50/20 (2018.01); A61B 5/7275 (2013.01);
Abstract

A method for determining a disease state transition path includes receiving a patient data having functional data and/or structural data related to a patient. Based on the patient data, a first disease state of a plurality of non-overlapping disease states each associated with a predetermined range of functional and/or structural degeneration values may be identified. A second, non-adjacent disease state of the plurality of disease states may be identified based on the patient data. A most probable path between the first disease state and the second disease state may be determined using a two dimensional continuous-time hidden Markov model.


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