The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Jan. 18, 2019
Case Western Reserve University, Cleveland, OH (US);
Anant Madabhushi, Shaker Heights, OH (US);
Mahdi Orooji, Cleveland, OH (US);
Niha Beig, Cleveland Heights, OH (US);
Vamsidhar Velcheti, Pepper Pike, OH (US);
Case Western Reserve University, Cleveland, OH (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Abstract
Methods, apparatus, and other embodiments predict response to immunotherapy from computed tomography (CT) images of a region of tissue demonstrating non-small cell lung cancer (NSCLC). One example apparatus includes a set of circuits that includes an image acquisition circuit that accesses a CT image of a region of tissue demonstrating cancerous pathology, a tumoral definition circuit that generates a tumoral surface boundary that defines a tumoral volume, a peritumoral segmentation circuit that generates a peritumoral region based on the tumoral surface boundary, and that segments the peritumoral region into a plurality of annular bands, a radiomics circuit that extracts a set of discriminative features from the tumoral volume and at least one of the plurality of annular bands, and a classification circuit that classifies the ROI as a responder or a non-responder, based, at least in part, on the set of discriminative features.