The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Jun. 24, 2016
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

John Haeseon Lee, Cambridge, MA (US);

Brian W. Anthony, Cambridge, MA (US);

Duane S. Boning, Belmont, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/06 (2006.01); G01N 29/46 (2006.01); G01N 29/032 (2006.01); G01N 15/10 (2006.01); A61B 8/00 (2006.01); A61B 8/08 (2006.01); G01N 29/24 (2006.01);
U.S. Cl.
CPC ...
G01N 15/06 (2013.01); A61B 8/4488 (2013.01); A61B 8/5207 (2013.01); A61B 8/5223 (2013.01); A61B 8/54 (2013.01); A61B 8/58 (2013.01); G01N 15/10 (2013.01); G01N 29/032 (2013.01); G01N 29/46 (2013.01); G01N 29/24 (2013.01); G01N 2015/1062 (2013.01); G01N 2291/02809 (2013.01); G01N 2291/044 (2013.01); G01N 2291/106 (2013.01);
Abstract

The systems and methods of the present disclosure are directed to ultrasound-based concentration measurement techniques in which both scatterer count and image volume are measured concurrently to provide absolute concentration measurements. In particular, through the techniques of the present disclosure, the effective thickness of an ultrasound beam can be determined based on the spreading of individual scatterers within ultrasound images. Based on the effective thickness of the ultrasound beam, the volume of the image and, thus, the concentration of particles in the image can be determined directly, without the need for estimation, approximation, or use of a reference sample.


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