The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Mar. 13, 2014
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Anna Marie Pyle, Guilford, CT (US);
Andrew Kohlway, Santa Clara, CA (US);
Dahai Luo, Proteos, SG;
David Rawling, San Mateo, CA (US);
Akiko Iwasaki, Guilford, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 38/21 (2006.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/713 (2013.01); A61K 38/212 (2013.01); A61K 38/215 (2013.01); A61K 45/06 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01);
Abstract
The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5' triphosphate or a 5′ diphosphate.