The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Mar. 06, 2020
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Samuel Henry Sternberg, New York, NY (US);

Sanne Eveline Klompe, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 9/22 (2006.01); C12N 15/63 (2006.01); C12N 15/90 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); C12N 15/63 (2013.01); C12N 15/902 (2013.01); C12N 2310/20 (2017.05);
Abstract

In certain embodiments, the present systems and methods use Tn7-like transposons that encode CRISPR-Cas systems for programmable, RNA-guided DNA integration. For example, the CRISPR-Cas machinery directs the Tn7 transposon-associated proteins to integrate DNA downstream of a target site (e.g., a genomic target site) recognized by a guide RNA (gRNA).


Find Patent Forward Citations

Sternberg, Samuel. (2021). Rna-guided dna integration using tn7-like transposons (U.S. Patent No. 10947534). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10947534

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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