The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Feb. 13, 2020
Applicant:
Sigma-aldrich Co. Llc, St. Louis, MO (US);
Inventor:
Fuqiang Chen, St. Louis, MO (US);
Assignee:
Sigma-Aldrich Co. LLC, St. Louis, MO (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/90 (2006.01); C12N 15/85 (2006.01); C07K 14/205 (2006.01); C07K 14/31 (2006.01); C07K 14/315 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C07K 14/205 (2013.01); C07K 14/31 (2013.01); C07K 14/315 (2013.01); C12N 15/113 (2013.01); C07K 2319/09 (2013.01);
Abstract
Engineered Cas9 systems are disclosed herein. For example, Cas9-marker fusion proteins are provided. Peptide linkers which facilitate fusion of heterologous proteins to CRISPR proteins in ways that preserve CRISPR functionality are also provided.