The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Oct. 20, 2016
Fujifilm Cellular Dynamics, Inc., Madison, WI (US);
Maksym A. Vodyanyk, Madison, WI (US);
Xin Zhang, Madison, WI (US);
Andrew J. Brandl, Madison, WI (US);
Deepika Rajesh, Madison, WI (US);
Bradley Swanson, Madison, WI (US);
Christie Munn, Madison, WI (US);
Sarah A. Burton, Madison, WI (US);
Wen Bo Wang, Madison, WI (US);
FUJIFILM Cellular Dynamics, Inc., Madison, WI (US);
Abstract
Provided herein are methods for the efficient in vitro differentiation of somatic cell-derived pluripotent stem cells to hematopoietic precursor cells, and the further differentiation of the hematopoietic precursor cells into immune cells of various myeloid or lymphoid lineages, particularly T cells, NK cells, and dendritic cells. The pluripotent cells may be maintained and differentiated under defined conditions; thus, the use of mouse feeder cells or serum is not required in certain embodiments for the differentiation of the hematopoietic precursor cells.