The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Sep. 12, 2016
Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same
Applicant:
The Research Foundation for the State University of New York, Syracuse, NY (US);
Inventors:
Assignee:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, Albany, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/50 (2017.01); A61K 9/51 (2006.01); A61K 9/107 (2006.01); C08G 83/00 (2006.01); A61K 47/60 (2017.01); A61P 37/08 (2006.01); C08G 65/329 (2006.01);
U.S. Cl.
CPC ...
C08G 83/002 (2013.01); A61K 9/107 (2013.01); A61K 9/5146 (2013.01); A61K 47/60 (2017.08); A61P 37/08 (2018.01); C08G 65/329 (2013.01); C08G 83/00 (2013.01); C08G 2650/32 (2013.01);
Abstract
Provided are multiply functional charged telodendrimers. The telodendrimers can be used for protein encapsulation and delivery. The charged telodendrimers may have one or more crosslinking groups (e.g., boronic acid/catechol reversible crosslinking groups). The telodendrimers can aggregate to form nanoparticles. Cargo such as combinations of proteins and other materials may be sequestered in the core of the nanoparticles via non-covalent or covalent interactions with the telodendrimers. Such nanoparticles may be used in protein delivery applications.