The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Sep. 05, 2016
Applicants:

Sorbonne Universite, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;

Assistance Publique—hopitaux DE Paris, Paris, FR;

Université DE Paris, Paris, FR;

Inventors:

Matthieu Sollogoub, Paris, FR;

Vincent Calvez, Paris, FR;

Anne-Geneviève Marcelin, Paris, FR;

Laurent Bouteiller, Bourg la Reine, FR;

Mickaël Menand, Alfortville, FR;

Pierre Evenou, Paris, FR;

Adélie Gothland, Paris, FR;

Dmitri Colesnic, Paris, FR;

Julien Rossignol, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/16 (2006.01); A61K 47/69 (2017.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C08B 37/0012 (2013.01); A61K 47/6951 (2017.08); C08B 37/0015 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01);
Abstract

The invention relates to a capped cyclodextrin-hydrophobic moiety conjugate, to a supramolecular polymer formed of capped cyclodextrin-hydrophobic moiety conjugates according to the invention and to a siRNA-cyclodextrin complex comprising a supramolecular polymer according to the invention. The invention also relates to a method for manufacturing the capped cyclodextrin-hydrophobic moiety conjugate, the supramolecular polymer, the siRNA-cyclodextrin complex according to the invention. The capped cyclodextrin-hydrophobic moiety conjugate of the invention comprises a capped cyclodextrin group and at least one hydrophobic moiety bound by a first linker to one of the carbon atoms of the cap. The invention can be used for various applications in particular in the pharmaceutical field.


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