The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Jul. 22, 2015
Applicant:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Inventors:

Mitsuhiro Iwamoto, Tokyo, JP;

Takahiro Yamaguchi, Tokyo, JP;

Yutaka Mori, Tokyo, JP;

Keiji Saito, Tokyo, JP;

Takeshi Honda, Tokyo, JP;

Takahiro Nagayama, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); C07K 14/58 (2006.01); A61K 38/00 (2006.01); A61K 47/65 (2017.01); A61K 47/60 (2017.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
C07K 14/58 (2013.01); A61K 38/00 (2013.01); A61K 38/2242 (2013.01); A61K 47/549 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08);
Abstract

The present invention provides a modified atrial natriuretic peptide that exhibits prolonged duration in blood and maintains cGMP elevating activity. The present invention provides a modified peptide in which at least one sugar substance is linked directly through a glycosidic bond or via a linker structure to at least one hANP peptide, or a pharmaceutically acceptable salt thereof, a medicament comprising the modified peptide or the salt thereof as an active ingredient, etc.


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