The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Jul. 21, 2016
Applicants:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Roche Nimblegen, Inc., Madison, WI (US);
Inventors:
Jeremy Beauchamp, Basel, CH;
Per-Ola Freskgard, Basel, CH;
Eric A. Kitas, Basel, CH;
Victor Lyamichev, Madison, WI (US);
Jigar Patel, Madison, WI (US);
Assignees:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
ROCHE NIMBLEGEN, INC., Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/08 (2006.01); C12N 9/64 (2006.01); A61P 25/28 (2006.01); A61K 38/08 (2019.01); A61K 38/10 (2006.01); A61K 38/55 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61P 25/28 (2018.01); C07K 7/08 (2013.01); C12N 9/6478 (2013.01); A61K 38/00 (2013.01); A61K 38/55 (2013.01);
Abstract
The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.