The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Jan. 14, 2019
Applicant:
National Yang-ming University, Taipei, TW;
Inventors:
C. Allen Chang, Taipei, TW;
Hsin-Ell Wang, Taipei, TW;
Jia-Je Li, Taipei, TW;
Shun-Fu Chang, Taipei, TW;
Roy Chen-Chih Wu, Taipei, TW;
Assignee:
NATIONAL YANG-MING UNIVERSITY, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/09 (2006.01); C12N 9/78 (2006.01); A61K 51/04 (2006.01); A61K 51/08 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0817 (2013.01); A61K 51/048 (2013.01); A61K 51/082 (2013.01); C12N 9/78 (2013.01); C07K 2319/01 (2013.01);
Abstract
The present invention provides a targeted prodrug enzyme fusion carrier comprising a targeted molecule and a prodrug enzyme. The targeted prodrug enzyme fusion carrier can effectively identify and bind to tumor cells and tumor-induced tumor angiogenesis. The targeted prodrug enzyme fusion carrier also has a targeted prodrug enzyme fusion protein and a theranostic system utilizing the method of in vivo nuclear medicine for the clinical diagnosis and treatment of individual patients with tumors.