The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Oct. 26, 2018
Council of Scientific & Industrial Research, New Delhi, IN;
Srivari Chandrasekhar, Hyderabad, IN;
Prathama Satyendra Mainkar, Hyderabad, IN;
Karre Nagaraju, Hyderabad, IN;
Togapur Pavan Kumar, Hyderabad, IN;
Ummanni Ramesh, Hyderabad, IN;
Kanchanapally Tejaswini, Hyderabad, IN;
Jerald Mahesh Kumar, Hyderabad, IN;
Katragadda Suresh Babu, Hyderabad, IN;
Boggavarapu Subrahmanya Sastry, Hyderabad, IN;
Debabrata Mukhopadhyay, Hyderabad, IN;
Abstract
The present invention relates to nimbolide analogs useful as anti-cancer agents and preparation thereof. Particularly the present invention relates to nimbolide analogs of general formula I. wherein, ring M is any ring selected from the group consisting of substituted or unsubstituted aryl, heteroaryl, cycloalkyl and heterocyclic; A and B are selected from the group consisting of C, O, N, S and H; R, R, R, R, Rand Rare selected from the group consisting of C1-C6 alkyl, aryl, heteroaryl, C1-C7 cycloalkyl, heteroalkyl, hydrogen, hydroxy, alkoxy, nitro, halogen, amino, alkylamino, aryl amino and cyano; wherein each of these groups may be further substituted with one or more substituents selected from the group consisting of hydrogen, hydroxy, halogen, cyano, alkyl amino, aryl amino, alkoxy, amino, nitro, aldehyde, carboxylic acid and ester.