The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Jun. 18, 2019
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Brent R. Stockwell, New York, NY (US);
Kenichi Shimada, Boston, MA (US);
Rachid Skouta, Amherst, MA (US);
Assignee:
The Trustees of Columbia University in the City of New York, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/15 (2006.01); C07D 401/12 (2006.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
C07C 311/15 (2013.01); C07D 401/12 (2013.01); C07D 407/12 (2013.01);
Abstract
The present invention provides, inter alia, a compound according to formula (I): Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for regulating GPX4 in a cell and methods for inducing ferroptosis in a cell.