The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Nov. 29, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Bin Liu, San Francisco, CA (US);
Scott Bidlingmaier, San Francisco, CA (US);
Yang Su, South San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 47/68 (2017.01); G01N 33/574 (2006.01); C12N 9/16 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); C07K 16/28 (2006.01); A61K 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6871 (2017.08); A61K 35/17 (2013.01); A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61P 35/00 (2018.01); C07K 16/2809 (2013.01); C07K 16/40 (2013.01); C12N 9/16 (2013.01); C12Y 301/03001 (2013.01); G01N 33/57407 (2013.01); G01N 33/57492 (2013.01); A61K 35/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/572 (2013.01); C07K 2317/31 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01);
Abstract
This invention provides antibodies directed against a highly specific and previously unrecognized marker for cancerous cells. In certain embodiments an isolated antibody or fragment thereof that specifically binds human placentally expressed ALPP and/or ALPPL2, but not ALPL and ALPI that are expressed outside the placenta is provided as well as immunoconjugates comprising such antibodies.