The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Nov. 15, 2017
Applicants:

Duke University, Durham, NC (US);

The University of Alabama AT Birmingham Research Foundation, Birmingham, AL (US);

Los Alamos National Security, Llc, Los Alamos, NM (US);

Inventors:

Barton F. Haynes, Durham, NC (US);

Feng Gao, Durham, NC (US);

Bette T. Korber, Los Alamos, NM (US);

Beatrice H. Hahn, Birmingham, AL (US);

George M. Shaw, Birmingham, AL (US);

Denise L. Monti, Birmingham, AL (US);

Ying Ying Li, Birmingham, AL (US);

Julie Decker, Birmingham, AL (US);

Hua-Xin Liao, Durham, NC (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C07K 14/005 (2006.01); C07K 16/42 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 16/4225 (2013.01); A61K 2039/53 (2013.01); A61K 2039/57 (2013.01); C12N 2740/15022 (2013.01); C12N 2740/15034 (2013.01); C12N 2740/16034 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16222 (2013.01); C12N 2740/16322 (2013.01);
Abstract

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.


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