The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Dec. 07, 2015
Applicant:

Seqirus Uk Limited, Berkshire, GB;

Inventors:

Christoph Haussmann, Marburg, DE;

Frank Hauschild, Marburg, DE;

Bjorn Jobst, Marburg, DE;

Assignee:

Seqirus UK Limited, Berkshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01); A61K 39/145 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/5252 (2013.01); C12N 2760/16034 (2013.01); C12N 2760/16051 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16163 (2013.01);
Abstract

A number of improvements for preparing vaccine antigens from disintegrated influenza viruses are disclosed. A splitting step can be followed by detergent exchange. Splitting can take place in the presence of a buffer with a higher ionic strength and/or in the presence of phosphate buffer.


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