The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 2021
Filed:
Oct. 30, 2017
Applicant:
Biomet Biologies, Llc, Warsaw, IN (US);
Inventors:
Jennifer E. Woodell-May, Warsaw, IN (US);
Joel C. Higgins, Claypool, IN (US);
William King, Warsaw, IN (US);
Assignee:
Biomet Biologics, LLC, Warsaw, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); C12N 5/0775 (2010.01); C12N 5/0786 (2010.01); A61K 35/16 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); C12N 5/0645 (2013.01); C12N 5/0667 (2013.01); A61K 35/16 (2013.01); C12N 2501/20 (2013.01); C12N 2502/1382 (2013.01);
Abstract
Methods of inducing a polarization of macrophages. The method includes obtaining a blood fraction, fractionating the blood fraction to produce a blood fraction, and contacting the blood fraction with a source of macrophages. A blood fraction including platelet-poor plasma polarizes the source of macrophages into M1 macrophages. A blood faction including a protein solution polarizes the source of macrophages into M2 macrophages.