The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 16, 2021

Filed:

Dec. 16, 2016
Applicant:

Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Masaharu Nakamura, Tokyo, JP;

Tsuyoshi Fukuda, Tokyo, JP;

Ken Yamakawa, Tokyo, JP;

Takuya Kato, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/282 (2006.01); A61K 31/555 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 47/62 (2017.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); C08G 65/334 (2006.01); C08G 69/08 (2006.01); C08G 69/48 (2006.01); C08G 81/00 (2006.01); C08L 71/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/555 (2013.01); A61K 31/282 (2013.01); A61K 47/541 (2017.08); A61K 47/60 (2017.08); A61K 47/62 (2017.08); A61K 47/645 (2017.08); A61P 35/00 (2018.01); C08G 65/3344 (2013.01); C08G 69/08 (2013.01); C08G 69/48 (2013.01); C08G 81/00 (2013.01); C08L 71/02 (2013.01); C08G 2261/126 (2013.01);
Abstract

A DDS preparation of a platinum complex, which exhibits a superior antitumor effect required as a medicine and reduced side effects, that is, a clinically usable DDS preparation of a platinum complex, which is conjugated to a polymer carrier that is different from conventional carriers, is desired. Provided is a polymer conjugate of a platinum(II) complex, the polymer conjugate including: a block copolymer having a polyethylene glycol structural moiety and a polyaspartic acid moiety or a polyglutamic acid moiety; a sulfoxide derivative introduced into a side-chain carboxyl group of the block copolymer; and a platinum(II) complex coordinate-bonded to a sulfoxide group of the sulfoxide derivative.


Find Patent Forward Citations

Loading…