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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10945994 B1

PDFFull Text
Expired
Date of Patent:
Mar. 16, 2021

Filed:

May. 12, 2016

Combinations comprising a pyrrolidine-2,5-dione ido1 inhibitor and an anti-body

Applicants:

Pfizer Inc., New York, NY (US);

Iteos Therapeutics, Charleroi, BE;

Inventors:

Manfred Kraus, San Diego, CA (US);

Sandra Cauwenberghs, Charleroi, BE;

Stefano Crosignani, Nivelles, BE;

Gregory Driessens, Charleroi, BE;

Assignees:

Pfizer Inc., New York, NY (US);

iTEOS THERAPEUTICS, Charleroi, BE;

Attorneys:

Howson and Howson LLP

Cathy Kodroff

Primary Examiner:

Theodore R Howell

Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61K 31/495 (2006.01); A61P 31/12 (2006.01); A61P 15/00 (2006.01); A61K 31/337 (2006.01); C07K 16/28 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 31/337 (2013.01); A61K 31/495 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61K 39/395 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 15/00 (2018.01); A61P 31/12 (2018.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 2039/505 (2013.01); A61K 2300/00 (2013.01);
Abstract

Combinations of an IDO1 inhibitor (e.g., a 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione compound), with an anti-PD1 antibody or anti-PD-L1 antibody, and an anti-4-1BB antibody, as selected anti-cancer or anti-viral agents are provided. Also provided are use of these combinations for the treatment and/or prevention of cancer and endometriosis.

Find Patent Forward Citations

Kraus, Manfred. (2021). Combinations comprising a pyrrolidine-2,5-dione ido1 inhibitor and an anti-body (U.S. Patent No. 10945994). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10945994

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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