The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Jan. 07, 2015
Shimadzu Corporation, Kyoto, JP;
Naoki Kaneko, Kyoto, JP;
Shimadzu Corporation, Kyoto, JP;
Abstract
Provided is a method for measuring amyloid precursor protein (APP) cleavage peptides including amyloid beta (Aβ) peptides. A method for measuring APP cleavage peptides in a blood sample includes the steps of: bringing a blood sample into contact with an antibody-immobilizing carrier in a binding solution to bind the antibody-immobilizing carrier and APP cleavage peptides contained in the blood sample, the antibody-immobilizing carrier including a carrier, and an antibody bound to the carrier and selected from the group consisting of an immunoglobulin having an antigen binding site capable of recognizing APP cleavage peptides and an immunoglobulin fragment containing an antigen binding site capable of recognizing APP cleavage peptides; washing a bound body of the antibody-immobilizing carrier and the APP cleavage peptides using a washing solution; dissociating the APP cleavage peptides from the antibody-immobilizing carrier using an acidic aqueous solution containing an organic solvent; and detecting the dissociated APP cleavage peptides.