The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2021

Filed:

Aug. 08, 2016
Applicant:

Agilent Technologies, Inc., Santa Clara, CA (US);

Inventors:

Mimi Healy, Houston, TX (US);

Xiyi Chen, Houston, TX (US);

Jinchun Wang, Houston, TX (US);

Weidong Wu, Houston, TX (US);

Sophia Petrichenko, Houston, TX (US);

Su Zhang, Houston, TX (US);

Stacie Frye, Houston, TX (US);

Assignee:

Agilent Technologies, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/53 (2006.01); G01N 33/58 (2006.01); G01N 33/533 (2006.01); B01L 3/00 (2006.01); G01N 1/30 (2006.01); G01N 1/31 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); B01L 3/502 (2013.01); G01N 1/30 (2013.01); G01N 1/312 (2013.01); G01N 33/533 (2013.01); G01N 33/5308 (2013.01); G01N 33/582 (2013.01); G01N 35/00029 (2013.01); B01L 2200/026 (2013.01); B01L 2300/0627 (2013.01); B01L 2400/082 (2013.01); G01N 2001/302 (2013.01); G01N 2035/00138 (2013.01);
Abstract

Provided herein are methods of using photocleavable labels for multiplex and serial antigen detection. The methods comprise detecting the presence of photocleavable labels, which are conjugated through functional linkers to antigen-binding complexes, which in turn non-covalently bind to antigens. The presence of a photocleavable label is indicative of the presence of an antigen specifically or selectively bound by an antigen-binding complex. Also provided are apparatuses for using photocleavable labels for multiplex and serial antigen detection.


Find Patent Forward Citations

Loading…