The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2021

Filed:

Nov. 12, 2019
Applicant:

Wyatt Technology Corporation, Goleta, CA (US);

Inventors:

Vincent Hsieh, Santa Barbara, CA (US);

Mario Yasa, Jr., Santa Barbara, CA (US);

Steven C. Minne, Santa Barbara, CA (US);

Assignee:

WYATT TECHNOLOGY CORPORATION, Goleta, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 21/51 (2006.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6452 (2013.01); G01N 21/474 (2013.01); G01N 21/51 (2013.01); G01N 2021/475 (2013.01); G01N 2021/4747 (2013.01); G01N 2021/6484 (2013.01); G01N 2201/0833 (2013.01);
Abstract

An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.


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