The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2021

Filed:

Mar. 13, 2017
Applicant:

Innovaprep Llc, Kansas City, MO (US);

Inventors:

Andrew Edward Page, Smithton, MO (US);

Zachary A. Packingham, Drexel, MO (US);

David Scott Alburty, Drexel, MO (US);

Alec D. Adolphson, Raymore, MO (US);

Assignee:

INNOVAPREP, LLC, Drexel, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/40 (2006.01); B01L 3/02 (2006.01); C12Q 1/24 (2006.01);
U.S. Cl.
CPC ...
G01N 1/4077 (2013.01); B01L 3/0275 (2013.01); C12Q 1/24 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0631 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/161 (2013.01); G01N 2001/4088 (2013.01);
Abstract

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.


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