The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Mar. 17, 2014
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Douglas A. Melton, Lexington, MA (US);
Sinisa Hrvatin, Cambridge, MA (US);
Shuibing C. Chen, Arlington, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 31/122 (2006.01); A61K 35/39 (2015.01); A61K 31/4178 (2006.01); A61K 45/06 (2006.01); A61K 31/404 (2006.01); A61K 31/4439 (2006.01); A61K 31/4045 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0676 (2013.01); A61K 31/122 (2013.01); A61K 31/404 (2013.01); A61K 31/4045 (2013.01); A61K 31/4178 (2013.01); A61K 31/4439 (2013.01); A61K 35/39 (2013.01); A61K 45/06 (2013.01); C12N 5/0678 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01);
Abstract
Disclosed herein are compositions and methods for the generation of insulin positive β cells, for example by exposing Pdx+ pancreatic progenitor cells to one or more compounds, and compositions and kits comprising isolated populations of insulin positive cells.