The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Nov. 08, 2018
Applicant:
National Institute of Advanced Industrial Science and Technology, Tokyo, JP;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07K 16/00 (2006.01); C07K 1/14 (2006.01); C07K 1/02 (2006.01); C07K 14/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 1/32 (2006.01); C07K 16/06 (2006.01); C07K 1/36 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 1/32 (2013.01); A61K 39/39591 (2013.01); C07K 1/02 (2013.01); C07K 1/145 (2013.01); C07K 1/22 (2013.01); C07K 1/36 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to a method for suppressing aggregation of polypeptide. Specifically, the present invention relates to a method for suppressing, in a solution comprising an antibody or an Fc region-containing protein, formation of an aggregate derived from an antibody or an Fc region-containing protein having a non-native conformation, the method comprising: the steps of (i) binding an AF.2A1 polypeptide or an analog thereof with an aggregate derived from the antibody or Fc region-containing protein having a non-native conformation in the solution; and (ii) collecting the aggregate bound to the polypeptide or analog thereof from the solution.