The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2021

Filed:

Jul. 19, 2019
Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Janus Schreiber Larsen, Holbæk, DK;

Florian Binder, Ingelheim am Rhein, DE;

Yunhai Cui, Ingelheim am Rhein, DE;

Oliver Hucke, Ingelheim am Rhein, DE;

Radoslaw Lipinski, Ingelheim am Rhein, DE;

Florian Montel, Ingelheim am Rhein, DE;

Markus Ostermeier, Ingelheim am Rhein, DE;

Alexandre Perera, Ingelheim am Rhein, DE;

Stefan Peters, Ingelheim am Rhein, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4192 (2006.01); A61K 31/501 (2006.01); A61K 31/4155 (2006.01); A61K 31/4178 (2006.01); A61K 31/4196 (2006.01); A61K 31/421 (2006.01); A61K 31/437 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61P 25/00 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to difluoromethyl-phenyl triazoles of general formula (I) which are modulators of GABAreceptors containing the α5 subunit, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.


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