IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10941126 B1

PDFFull Text
Date of Patent:
Mar. 09, 2021

Filed:

Jan. 19, 2018

Bridged bicycloalkyl-substituted aminothiazoles and their methods of use

Applicant:

Temple University—of the Commonwealth System of Higher Education, Philadelphia, PA (US);

Inventors:

Wayne C. Childers, New Hope, PA (US);

Magid A. Abou-Gharbia, Exton, PA (US);

George C. Morton, Collegeville, PA (US);

Jean-Pierre J. Issa, Philadelphia, PA (US);

Hanghang Zhang, Philadelphia, PA (US);

Assignee:

TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, Philadelphia, PA (US);

Attorney:

Riverside Law LLP

Primary Examiner:

Samantha L Shterengarts

Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/427 (2006.01); C07D 277/42 (2006.01); A61P 35/00 (2006.01); C07D 417/06 (2006.01); A61K 31/05 (2006.01); A61K 31/11 (2006.01); A61K 31/166 (2006.01); A61K 31/167 (2006.01); A61K 31/352 (2006.01); A61K 31/365 (2006.01); A61K 31/404 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/5377 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07D 277/42 (2013.01); A61P 35/00 (2018.01); C07D 417/06 (2013.01); A61K 31/05 (2013.01); A61K 31/11 (2013.01); A61K 31/166 (2013.01); A61K 31/167 (2013.01); A61K 31/352 (2013.01); A61K 31/365 (2013.01); A61K 31/404 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/5377 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01);
Abstract

The present invention includes novel bridged bicycloalkyl-substituted aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.

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