The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Nov. 12, 2018
Applicant:
Janssen Sciences Ireland Uc, Little Island, Co Cork, IE;
Inventors:
Koen Vandyck, Paal-Beringen, BE;
Stefaan Julien Last, Beveren, BE;
Pierre Jean-Marie Bernard Raboisson, Wavre, BE;
Assignee:
Janssen Sciences Ireland UC, Little Island, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/37 (2006.01); A61K 31/18 (2006.01); C07C 311/16 (2006.01); C07C 311/17 (2006.01); C07C 311/18 (2006.01); C07C 311/19 (2006.01); C07C 317/28 (2006.01); A61K 45/06 (2006.01); A61K 31/27 (2006.01); A61K 31/277 (2006.01);
U.S. Cl.
CPC ...
C07C 311/37 (2013.01); A61K 31/18 (2013.01); A61K 31/27 (2013.01); A61K 31/277 (2013.01); A61K 45/06 (2013.01); C07C 311/16 (2013.01); C07C 311/17 (2013.01); C07C 311/18 (2013.01); C07C 311/19 (2013.01); C07C 317/28 (2013.01);
Abstract
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, salts, hydrates and solvates thereof, wherein R, R, Rand Rhave the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.