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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10940235 B1

PDFFull Text
Date of Patent:
Mar. 09, 2021

Filed:

Apr. 15, 2016

Biocompatible implants for nerve re-generation and methods of use thereof

Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Joachim B. Kohn, Piscataway, NJ (US);

Basak Clements, Newbury Park, CA (US);

Mindy Ezra Sadik, Gainesville, FL (US);

Assignee:

RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);

Attorney:

Fox Rothschild LLP

Primary Examiner:

Diane D Yabut

Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61B 17/11 (2006.01); C08G 64/12 (2006.01); A61L 27/20 (2006.01); A61L 27/24 (2006.01); A61L 27/52 (2006.01); A61L 27/16 (2006.01); A61L 27/34 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); C08G 69/40 (2006.01); C08G 69/44 (2006.01); C08G 64/18 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61B 17/1128 (2013.01); A61L 27/16 (2013.01); A61L 27/20 (2013.01); A61L 27/24 (2013.01); A61L 27/34 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); C08G 64/12 (2013.01); C08G 64/183 (2013.01); C08G 69/40 (2013.01); C08G 69/44 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/00893 (2013.01); A61B 2017/1132 (2013.01); A61L 2400/06 (2013.01); A61L 2430/32 (2013.01); C08G 2210/00 (2013.01); C08G 2230/00 (2013.01);
Abstract

A biocompatible nerve conduit for nerve re-generation, wherein a porous fiber tube is coated with a bioresorbable hydrogel, with the fibers being formed from a polymer that supports nerve regeneration by preferential adsorption of endogenous proteins and braided with pores in the range from 5 to 200 micrometers using a kink-resistant braiding pattern and the hydro gel coating material and thickness being selected to control the overall porosity, so that nutrients and oxygen can diffuse through said hydrogel coating but the infiltration of fibrous tissue through the coating is prevented.

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