The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Dec. 02, 2016
Xiamen University, Xiamen, CN;
Xiamen Innovax Biotech Co., Ltd., Xiamen, CN;
Shaowei Li, Xiamen, CN;
Zhihai Li, Xiamen, CN;
Shuo Song, Xiamen, CN;
Maozhou He, Xiamen, CN;
Ying Gu, Xiamen, CN;
Ningshao Xia, Xiamen, CN;
Xiamen University, Xiamen, CN;
Xiamen Innovax Biotech Co., Ltd., Xiamen, CN;
Abstract
Provided are a mutated HPV58 L1 protein or a variant thereof, a sequence encoding the same, a method for preparing the same, and a virus-like particle comprising the same, wherein the protein or a variant thereof and the virus-like particle can induce the generation of neutralizing antibodies against at least two HPV types, and therefore can be used to prevent infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum. The invention further relates to the use of the protein and the virus-like particle in the manufacture of a pharmaceutical composition or a vaccine for preventing infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum.