The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
Feb. 02, 2018
Applicant:
Mcmaster University, Hamilton, CA;
Inventors:
Eric Brown, Oakville, CA;
Maya Farha, Ancaster, CA;
Craig MacNair, Ancaster, CA;
Jonathan Stokes, Cambridge, MA (US);
Assignee:
McMaster University, Hamilton, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/00 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/18 (2006.01); A61P 31/22 (2006.01); A61P 33/02 (2006.01); A61P 31/16 (2006.01); A61K 31/431 (2006.01);
U.S. Cl.
CPC ...
A61K 33/00 (2013.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01); A61P 31/16 (2018.01); A61P 31/18 (2018.01); A61P 31/22 (2018.01); A61P 33/02 (2018.01); A61K 31/431 (2013.01); A61K 2300/00 (2013.01); Y02A 50/30 (2018.01);
Abstract
Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.