The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Apr. 04, 2019
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Sylvie Breton, Belmont, NH (US);
Dennis Brown, Natick, MA (US);
Anie Azroyan, Boulogne-Billancourt, FR;
Virna F. Cortez-Retamozo, Cambridge, MA (US);
Mikael Pittet, Charlestown, MA (US);
Assignee:
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/74 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/66 (2006.01); A61K 31/451 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/74 (2013.01); A61K 31/451 (2013.01); C07K 16/28 (2013.01); G01N 33/5308 (2013.01); G01N 33/566 (2013.01); G01N 33/66 (2013.01); A61K 2039/505 (2013.01); C07K 2317/20 (2013.01); C07K 2317/76 (2013.01); G01N 2333/726 (2013.01); G01N 2800/347 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7095 (2013.01);
Abstract
The present disclosure relates to assays and methods for the detection of renal inflammation by measuring the level of P2Y14 and/or UDP-glucose in a sample from a subject, such as a urine sample. The present disclosure also relates to methods for the treatment of renal inflammation by administering a P2Y14 inhibitor.