The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Dec. 13, 2017
Ventana Medical Systems, Inc., Tucson, AZ (US);
University of Cincinnati, Cincinnati, OH (US);
Mana Mirza, New Dehli, IN;
Elizabeth Shaughnessy, Cincinnati, OH (US);
John K. Hurley, Tucson, AZ (US);
Kristie A. Vanpatten, Oro Valley, AZ (US);
Gary Pestano, Oro Valley, AZ (US);
Georg F. Weber, Cincinnati, OH (US);
VENTANA MEDICAL SYSTEMS, INC., Tucson, AZ (US);
UNIVERSITY OF CINCINNATI, Cincinnati, OH (US);
Abstract
The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (DCIS). By determining the grade, stage, or aggressiveness of a cancer, appropriate therapeutic regiments can be selected and administered to the patient with the cancer. The method includes detecting osteopontin-c (OPN-c), wherein the presence of high amounts of OPN-c in the cancer sample indicates that the subject has a more aggressive form of cancer (e.g., grade 3).