The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Apr. 23, 2018
Applicants:
Illumina, Inc., San Diego, CA (US);
Illumina Cambridge Limited, Nr Saffron Walden, GB;
Inventors:
Eric Hans Vermaas, San Diego, CA (US);
Mahdieh Khosroheidari, San Diego, CA (US);
Claire Bevis-Mott, Nr Saffron Walden, GB;
Assignee:
Illumina, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/6834 (2018.01); C12Q 1/6855 (2018.01); C12Q 1/6806 (2018.01); C40B 50/18 (2006.01); C40B 20/04 (2006.01); C40B 50/16 (2006.01); C12Q 1/6809 (2018.01); C12Q 1/6816 (2018.01); C40B 70/00 (2006.01); C40B 80/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6855 (2013.01); C40B 20/04 (2013.01); C40B 50/16 (2013.01); C40B 50/18 (2013.01); C40B 70/00 (2013.01); C40B 80/00 (2013.01);
Abstract
The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by modifying or blocking 5' and 3′ ends of pooled indexed polynucleotides from multiple samples, with an optional exonuclease treatment, prior to amplification and sequencing.