The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2021

Filed:

May. 08, 2018
Applicant:

Humacyte, Inc., Durham, NC (US);

Inventors:

Shannon L. M. Dahl, Durham, NC (US);

Laura E. Niklason, Durham, NC (US);

Justin T. Strader, Cary, NC (US);

William E. Tente, Seekonk, MA (US);

Joseph J. Lundquist, Durham, NC (US);

Assignee:

Humacyte, Inc., Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61L 27/34 (2006.01); A61F 2/06 (2013.01); A61F 2/04 (2013.01); B29C 53/00 (2006.01); B29C 53/36 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); B29K 67/00 (2006.01); B29K 105/00 (2006.01); B29L 23/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); A61F 2/04 (2013.01); A61F 2/06 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/34 (2013.01); A61L 27/3633 (2013.01); A61L 27/38 (2013.01); A61L 27/3895 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); B29C 53/005 (2013.01); B29C 53/36 (2013.01); A61F 2002/047 (2013.01); A61F 2002/048 (2013.01); B29K 2067/043 (2013.01); B29K 2105/256 (2013.01); B29K 2995/006 (2013.01); B29K 2995/0056 (2013.01); B29L 2023/00 (2013.01); B29L 2031/7532 (2013.01); C12N 2533/30 (2013.01); C12N 2533/40 (2013.01); Y10T 156/1038 (2015.01);
Abstract

The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.


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