The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
May. 09, 2019
Shin-etsu Chemical Co., Ltd., Tokyo, JP;
Junichi Matsubara, Niigata, JP;
Mitsuhiro Yoshida, Niigata, JP;
SHIN-ETSU CHEMICAL CO., LTD., Tokyo, JP;
Abstract
There is provided a method for producing hypromellose phthalate (HPMCP) which exhibits an excellent solubility when dissolved in a solvent, while suppressing formation of undissolved matter. More specifically, there is provided a method for producing HPMCP, including an esterification step of esterifying hypromellose dissolved in glacial acetic acid with phthalic anhydride in the presence of sodium acetate at a temperature of from 75 to 100° C. to obtain a reaction product solution; a cooling step of cooling the reaction product solution to 70° C. or lower; and a precipitation step of mixing the cooled reaction product solution with water of from 0 to 40° C. to obtain a suspension of precipitated HPMCP.