The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2021

Filed:

Oct. 12, 2017
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Qingjie Liu, Newtown, PA (US);

T. G. Murali Dhar, Newtown, PA (US);

Lan-ying Qin, Plainsboro, NJ (US);

Lyndon A. M. Cornelius, Jackson, NJ (US);

Hai-Yun Xiao, Belle Mead, NJ (US);

Jianqing Li, Guilford, CT (US);

Robert J. Cherney, Newtown, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 491/147 (2013.01);
Abstract

There are described RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ Gamma activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ Gamma activity, for example, autoimmune and/or inflammatory disorders.


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