The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Nov. 25, 2016
Applicant:
Lieber Institute for Brain Development, Baltimore, MD (US);
Inventors:
James Barrow, Arnold, MD (US);
Glen Ernst, Bear, DE (US);
Dominique Swinnen, Braine l'Alleud, BE;
Florian Montel, Meitingen, DE;
Sabine Defays, Tubize, BE;
Yifang Huang, Lansdale, PA (US);
Pablo de León, Baltimore, MD (US);
Michael Steven Poslusney, Owings Mills, MD (US);
Assignee:
LIEBER INSTITUTE, INC., Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 25/00 (2006.01); A61K 31/165 (2006.01); A61K 31/197 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/165 (2013.01); A61K 31/197 (2013.01); A61K 31/4985 (2013.01); A61P 25/00 (2018.01);
Abstract
Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.