The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2021

Filed:

Jul. 29, 2020
Applicants:

Aragon Pharmaceuticals, Inc., San Diego, CA (US);

Sloan-kettering Institute for Cancer Research, New York, NY (US);

Inventors:

Anna Dihas, Basel, CH;

Mark R. Herbert, San Diego, CA (US);

Ouathek Ouerfelli, New York, NY (US);

Nicholas D. Smith, San Diego, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01);
Abstract

Described herein are amorphous and crystalline forms of the androgen receptor modulator 4-[7-(6-cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide. Also described are pharmaceutical compositions suitable for administration to a mammal that include the androgen receptor modulator, and methods of using the androgen receptor modulator, alone and in combination with other compounds, for treating diseases or conditions that are associated with androgen receptor activity.


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