The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Oct. 19, 2011
David L. Kaplan, Concord, MA (US);
Konstantinos Tsioris, Somerville, MA (US);
Fiorenzo G. Omenetto, Lexington, MA (US);
Eleanor M. Pritchard, New Orleans, LA (US);
David L. Kaplan, Concord, MA (US);
Konstantinos Tsioris, Somerville, MA (US);
Fiorenzo G. Omenetto, Lexington, MA (US);
Eleanor M. Pritchard, New Orleans, LA (US);
Trustees of Tufts College, Medford, MA (US);
Abstract
A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.