The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2021

Filed:

Jul. 14, 2016
Applicant:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Inventors:

Yair Reisner, Old Jaffa, IL;

Noga Or-Geva, Rehovot, IL;

Eran Ophir, Rehovot, IL;

Yaki Eidelstein, Rehovot, IL;

Rotem Gidron Budovsky, Rehovot, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 31/00 (2006.01); A61P 35/04 (2006.01); A61K 39/00 (2006.01); C12N 5/078 (2010.01); C12N 5/0783 (2010.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 39/001 (2013.01); A61K 35/17 (2013.01); A61K 39/39566 (2013.01); A61P 31/00 (2018.01); A61P 35/04 (2018.01); C07K 16/2896 (2013.01); C12N 5/0636 (2013.01); C12N 5/0637 (2013.01); C12N 5/0648 (2013.01); A61K 2035/122 (2013.01); A61K 2039/5158 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01); Y02A 50/30 (2018.01);
Abstract

A method of transplantation is disclosed. The method comprising administering to a subject in need of transplantation of cells in suspension, a therapeutically effective amount of anti-third party cells having a central memory T-lymphocyte (Tcm) phenotype, said anti-third party cells being tolerance-inducing cells and capable of homing to the lymph nodes following transplantation, wherein said cells in suspension comprise non-hematopoietic cells or hematopoietic cells which are not stem cells. Methods of treating and kits are also provided.


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