The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Feb. 22, 2018
Applicant:
Albert Einstein College of Medicine, Bronx, NY (US);
Inventors:
Sridhar Mani, Riverdale, NY (US);
Subhajit Mukherjee, Bronx, NY (US);
Assignee:
Albert Einstein College of Medicine, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61K 31/405 (2006.01); A61K 35/742 (2015.01); C07D 211/56 (2006.01); C07D 211/92 (2006.01); G16H 50/20 (2018.01); G06F 19/00 (2018.01); A61K 35/741 (2015.01); C12Q 1/02 (2006.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/742 (2013.01); A61K 35/741 (2013.01); C07D 211/56 (2013.01); C07D 211/92 (2013.01); C12Q 1/025 (2013.01); G06F 19/00 (2013.01); G16H 50/20 (2018.01); A61K 2035/115 (2013.01); Y02A 90/10 (2018.01); Y10T 436/145555 (2015.01);
Abstract
Methods are disclosed for treating and preventing gut barrier dysfunction or an illness associated with gut barrier dysfunction in a subject comprising administering to the subject bacterium that produce an indole or an indole metabolite and for identifying compounds and bacteria for use in treatment and prevention of gut barrier dysfunction or an illness associated with gut barrier dysfunction.