The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2021

Filed:

Oct. 17, 2017
Applicant:

Dynebio Inc., Seongnam-si, KR;

Inventors:

Je Hyeon Lee, Seongnam-si, KR;

Eun Joo Kim, Seongnam-si, KR;

Kyoung Woon Kim, Seoul, KR;

Assignee:

DYNEBIO INC., Seongnam-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/729 (2006.01); A23L 29/30 (2016.01); A23L 33/125 (2016.01); A61P 19/02 (2006.01); A61K 31/702 (2006.01); C12P 19/04 (2006.01); A23L 33/10 (2016.01);
U.S. Cl.
CPC ...
A61K 31/729 (2013.01); A23L 29/30 (2016.08); A23L 33/10 (2016.08); A23L 33/125 (2016.08); A61K 31/702 (2013.01); A61P 19/02 (2018.01); C12P 19/04 (2013.01);
Abstract

Provided in the present invention is a novel use of composition containing a neoagarooligosaccharide mixture as an active ingredient. The neoagarooligosaccharide mixture and the like as an active ingredient of the composition according to the present invention can reduce the expression of RANKL, an osteoclast inducer, or IL-6, an inflammatory cytokine, and effectively inhibit differentiation of monocytes into osteoclasts. Thus, the composition according to the present invention may be used as a medicine or functional food for preventing, alleviating, or treating arthritis (especially rheumatoid arthritis). Further, the active ingredient of the composition according to the present invention can be obtained by an enzyme reaction between a readily available substrate such as agar or agarose and DagA as a beta-agarase derived from. Thus, it can be produced at a relatively low cost and can easily be ingested by anyone because it has no side effects.


Find Patent Forward Citations

Loading…