The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Nov. 24, 2016
Hebei Medfaith Pharmaceutical Technology Co., Ltd., Shijiazhuang, CN;
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, CN;
Hongwei Tian, Shenyang, CN;
Xingang Wang, Shenyang, CN;
Rongguang Shao, Beijing, CN;
Yucheng Wang, Beijing, CN;
Naren Li, Beijing, CN;
Shi-Ying Cai, Cheshire, CT (US);
Hongwei He, Beijing, CN;
Juxian Wang, Beijing, CN;
Shuangshuang Zhao, Beijing, CN;
Maoxu Ge, Beijing, CN;
Jinfeng Ren, Beijing, CN;
Hebei Medfaith Pharmaceutical Technology Co., Ltd., Shijiazhuang, CN;
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, CN;
Abstract
The invention belongs to the technical field of medicines. In particular, the invention relates to use of (benzenesulfonamido) benzamide compounds for inhibiting liver fibrosis, or preventing and/or treating a liver injury, or improving a liver function, or preventing and/or treating a liver disease associated with liver fibrosis, for modulating (e.g. reducing) the content of collagen (e.g. type I collagen) in liver tissue, for modulating (e.g. inhibiting) the activity of COL1A1 promoter in a cell, and for modulating (e.g. inhibiting) expression level of a gene associated with liver fibrosis in a cell.