The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Jul. 10, 2017
Jang-jih LU, Taipei, TW;
Chun-hsien Chen, Taoyuan, TW;
Hsin-yao Wang, Chiayi, TW;
Tsui-ping Liu, New Taipei, TW;
Jang-Jih Lu, Taipei, TW;
Chun-Hsien Chen, Taoyuan, TW;
Hsin-Yao Wang, Chiayi, TW;
Tsui-Ping Liu, New Taipei, TW;
CHANG GUNG MEMORIAL HOSPITAL, LINKOU, Taoyuan, TW;
CHANG GUNG UNIVERSITY, Taoyuan, TW;
Abstract
A method of creating characteristic peak profiles of mass spectra and identification model for analyzing and identifying microorganisms are provided. MALDI-TOF MS data of microorganisms having the same feature are gathered. Discretization of the data is performed. Density-based clustering is used to find m/z values of spectral peaks with high probability of occurrence from the discretized data. A characteristic MS peak profile is created for every specific feature of microorganisms. Every such a characteristic profile forms a feature template. The mass spectrum of each known isolate is matched against all the feature templates and a number of matched vectors are obtained. The matched vectors are then concatenated into a single 'integrated vector.' Then, a machine learning method and the integrated vectors generated from all known isolates are used to create a classification model for microorganism identification.