The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Nov. 28, 2018
Applicant:

Cytoviva, Inc., Auburn, AL (US);

Inventors:

James M. Beach, Auburn, AL (US);

Samuel M. Lawrence, Auburn, AL (US);

Byron J. Cheatham, Auburn, AL (US);

James L. Uertz, Auburn, AL (US);

Robert P. Dougherty, Bellevue, WA (US);

Assignee:

CYTOVIVA, INC., Auburn, AL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06T 17/00 (2006.01); G02B 21/10 (2006.01); G02B 21/36 (2006.01); G01N 21/64 (2006.01); G02B 21/16 (2006.01); G06T 5/00 (2006.01); G06T 7/00 (2017.01); G06T 15/08 (2011.01); G06T 15/50 (2011.01); G01N 15/00 (2006.01); G01N 15/14 (2006.01);
U.S. Cl.
CPC ...
G06T 17/00 (2013.01); G01N 21/6458 (2013.01); G02B 21/10 (2013.01); G02B 21/16 (2013.01); G02B 21/367 (2013.01); G06T 5/004 (2013.01); G06T 7/0012 (2013.01); G06T 15/08 (2013.01); G06T 15/506 (2013.01); G01N 2015/0038 (2013.01); G01N 2015/1445 (2013.01); G06T 2200/04 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30004 (2013.01); G06T 2210/41 (2013.01);
Abstract

Disclosed are various embodiments for methods and systems for three-dimensional imaging of subject particles in media through use of dark-field microscopy. Some examples, among others, include a method for obtaining a three-dimensional (3D) volume image of a sample, a method for determining a 3D location of at least one subject particle within a sample, a method for determining at least one spatial correlation between a location of at least one subject particle and a location of at least one cell structure within a cell and/or other similar biological or nonbiological structure, a method of displaying a location of at least one subject particle, method for increasing the dynamic range of a 3D image acquired from samples containing weak and strong sources of light, and method for sharpening a 3D image in a vertical direction.


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