The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Jun. 04, 2018
Ventana Medical Systems, Inc., Tucson, AZ (US);
Michael Barnes, Oro Valley, AZ (US);
Joerg Bredno, San Francisco, CA (US);
Christophe Chefd'hotel, San Jose, CA (US);
Srinivas Chukka, San Jose, CA (US);
Kien Nguyen, Ho Chi Minh, VN;
Anindya Sarkar, Milpitas, CA (US);
VENTANA MEDICAL SYSTEMS, INC., Tucson, AZ (US);
Abstract
Methods and systems for generating a heat map that reduces bias in selecting FOVs are disclosed. Some disclosed methods include annotating a primary stained image, registering the annotation to a secondary serial specific stained image, using an image analysis algorithm to compute a scoring criteria specific to the tissue and assay type for tiled regions in the image, using a sliding window in the annotated tumor region to compute values for each pixel in a heat map which correlate to the specific scoring criteria, displaying the heat map at low resolution, ranking and selecting hot spots, selecting FOVs from the hot spot regions which results in displaying the slide-level score for the FOVs. The systems comprise, among other things, software configured to perform the referenced method.