The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Jun. 26, 2015
Applicant:
Northeastern University, Boston, MA (US);
Inventors:
Assignee:
Northeastern University, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B01L 3/00 (2006.01); C12M 1/12 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12N 5/09 (2010.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); B01L 3/50273 (2013.01); B01L 3/502761 (2013.01); B01L 3/502784 (2013.01); C12M 23/16 (2013.01); C12M 25/01 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); C12N 5/0693 (2013.01); G01N 33/5044 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/168 (2013.01); B01L 2300/18 (2013.01); B01L 2400/0478 (2013.01); C12N 2502/11 (2013.01); C12N 2513/00 (2013.01); C12N 2533/74 (2013.01);
Abstract
A microfluidic device provides high throughput generation and analysis of defined three-dimensional cell spheroids with controlled geometry, size, and cell composition. The cell spheroids of the invention mimic tumor microenvironments, including pathophysiological gradients, cell composition, and heterogeneity of the tumor mass mimicking the resistance to drug penetration providing more realistic drug response. The device is used to test the effects of antitumor agents.
Konry, Tania. (2021). Microfluidic device and method for analysis of tumor cell microenvironments (U.S. Patent No. 10928382). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10928382
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile