The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Nov. 10, 2016
Applicants:
Celator Pharmaceuticals, Inc., Palo Alto, CA (US);
Oregon Health & Science University, Portland, OR (US);
Inventors:
Max Gordon, Portland, OR (US);
Paul Tardi, Surrey, CA;
Jeffrey Tyner, Portland, OR (US);
Lawrence Mayer, North Vancouver, CA;
Assignees:
Celator Pharmaceuticals, Inc., Palo Alto, CA (US);
Oreoon Health & Science University, Portland, OR (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 31/4709 (2006.01); A61K 31/517 (2006.01); A61K 31/496 (2006.01); A61K 31/44 (2006.01); A61K 31/506 (2006.01); A61K 31/553 (2006.01); A61P 35/02 (2006.01); A61K 31/407 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/68 (2018.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 9/127 (2013.01); A61K 31/407 (2013.01); A61K 31/44 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 31/553 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61P 35/02 (2018.01); C12Q 1/68 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Diagnostic methods for identifying cancer bearing subjects appropriate for treatment with CPX-351 include genetic and ex vivo testing of cells from a candidate subject. Combination treatment with CPX-351 and FLT-3 inhibitors improve CPX-351 uptake and toxicity.